This peripheral blood film is from a 3-month-old patient with lymphocytosis apparently due to infection. the white blood cell count in this case was 64,000 / cu mm, of which 80% were lymphocytes. As you can see, the lymphocytes have a normal cytologic appearance, and this blood picture cannot be distinguished from that seen in typical CLL. The age of the patient, however, is against a diagnosis of CLL, since this disease rarely occurs in persons under 30 years old. The duration of the lymphocytosis also may be used to distinguish CLL from other conditions of lymphocytosis, although chronic infections such as tuberculosis can cause a sustained lymphocytosis.
Course Section: 07. Lymphocytic Leukemia: Acute and Chronic
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