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Slide 1
This program, Lymphocytic Leukemia: Acute and Chronic, provides information about how to use Wright's stained peripheral blood and bone marrow to recognize acute lymphocytic leukemia (ALL) and to distinguish this condition from acute nonlymphocytic leukemia (ANLL) and from chronic lymphocytic leukemia (CLL). The French-American-British (FAB) subclassification of ALL and some morphologic variants of CLL will be presented. Features used to distinguish these leukemias from other diseases, such as infectious mononucleosis, will be briefly covered. The classification of lymphocytic disorders has rapidly evolved in recent years with the introduction of new methods for studying lymphocytes. A few slides in this program will summarize and illustrate some of these methods, which promise to help clarify the current confusion in the study of lymphocytic leukemias.

The next four slides and six slides later in the program are questions for you to answer. As you proceed through these slides, you will note that all the microscopic fields are thin areas of peripheral blood or bone marrow. Lymphocytes should always be viewed in thin areas of blood smears so that the pattern of the nuclear chromatin and the presence and appearance of nucleoli can best be appreciated.


HEMATOLOGY
Course Section: 07. Lymphocytic Leukemia: Acute and Chronic
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