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Slide 11
The lymphoblasts in this bone marrow aspirate are consistently large, and the nuclei are fairly regular in size and shape. Prominent nucleoli are present in many of the nuclei. Most striking is the abundant basophilic cytoplasm, which is markedly vacuolated. Vacuoles may occur in the other two types of ALL, but in L3 this feature is most marked and consistently seen.

HEMATOLOGY
Course Section: 07. Lymphocytic Leukemia: Acute and Chronic
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