This slide shows the peripheral blood film of a patient with well-differentiated lymphocytic lymphoma. It cannot definitely be distinguished from the blood of a patient with CLL, although many of the lymphocytes with deeply clefted nuclei would be labeled abnormal by us. Not all lymphomas have a tendency to become leukemic (Hodgkin's disease rarely does), but when lymphocytic lymphomas do spread to the blood stream, the cytologic picture can range from that seen in ALL to that in CLL.
Course Section: 07. Lymphocytic Leukemia: Acute and Chronic
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