This slide shows a bone marrow aspirate heavily infiltrated with CLL lymphocytes. When bone marrow aspirates are obtained from patients with CLL, an increased number of Iymphocytes is generally found, although occasionally the lymphocyte count is completely normal. The cytology of the lymphocytes is often unremarkable. Nonlymphoid bone marrow elements are generally not qualitatively abnormal, but their number may be reduced if the lymphocytic infiltration is substantial. An eosinophilia may occur for unknown reasons in a few cases, and erythroid hyperplasia also may be noted, especially if a hemolytic anemia is associated with the CLL.
Course Section: 07. Lymphocytic Leukemia: Acute and Chronic
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