Monocytes are phagocytic cells and may contain many vacuoles. In fact, in blood that has been collected in an anticoagulant and left standing for any length of time, the monocytes become vacuolated much more often than not. One criterion for identifying monocytes in blood collected in EDTA is the presence of vacuoles. If you see vacuoles in a cell, you automatically think first of a monocyte.
Course Section: 03. Blood Smears Stained with Wright's Stain
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