The cell on this slide is a basophil. Basophils are easily recognized because they have bluish-black granules that vary in size. Usually the granules overlie the nucleus so that the lobes are obscured. The basophilic granules are alcohol-soluble and may dissolve during the staining process. This is particularly evident if slides are dipped in absolute methyl alcohol before adding Wright's stain. Basophils are the rarest of the cells in normal blood. They are increased in number most often in patients with chronic myelocytic leukemia and myelofibrosis.
Course Section: 03. Blood Smears Stained with Wright's Stain
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