Another way the Howell-Jolly body may be formed is demonstrated in this slide. The nucleus of the cell in the center of the slide appears to be undergoing fragmentation (karyorrhexis). Pieces of the nuclear chromatin appear to have broken away. These may become Howell-Jolly bodies and may be left within the cell when the remainder of the nucleus is extruded.
Course Section: 02. Inclusions Found in Red Blood Cells
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