Six cells in this slide contain blue inclusion bodies. Several cells contain more than one and the cell on the far right appears to have a cluster of bodies. These are Pappenheimer bodies. Clusters of granules are always indicative of Pappenheimer bodies. They are smaller than Howell-Jolly bodies and stain blue rather than bluish-red. Pappenheimer bodies contain iron (nonhemoglobin or ionic iron). To verify their identity, their iron content is stained by Perls' reaction, sometimes called Prussian blue stain.
Course Section: 02. Inclusions Found in Red Blood Cells
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