If you look closely, you may see the dustlike particles in the cell indicated by the arrow. These are azurophilic granules, seen in polychromatic or young red cells (reticulocytes). They are nuclear remnants after fragmentation of the nucleus. It is difficult to distinguish them from basophilic stippiing, as both stain bluish and are seen in polychromatic cells. About the only difference is the size of the particles; the azurophilic granules are smaller. They are seen in blood smears of patients with severe anemia.
Course Section: 02. Inclusions Found in Red Blood Cells
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