The cell indicated by the arrow is a prolymphocyte observed in the blood of a patient with prolymphocytic leukemia. It is a large cell with an N:C ratio of approximately 4:1. The nuclear chromatin is fine but beginning to aggregate. There is a prominent nucleolus with a well-defined nucleolar membrane. The cytoplasm is basophilic with a light area around the nucleus. The second cell in the field is a normal mature lymphocyte.
Course Section: 04. Immature Cells in the Granulocytic - Monocytic - and Lymphocytic Series
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