Table 3 compares the clinical presentations and laboratory parameters of BMG, MM, and WM. BMG is a common condition; approximately 1% of an unselected population has a monoclonal Ig, and the incidence increases with age. WM gets its name from the first person to have described the disease and from the large size of the monoclonal IgM that is characteristic of the disease. The large IgM also is responsible for the hyperviscosity syndrome seen in WM. The suppression of normal Ig (hypogammaglobulinemia) in MM and WM is partly responsible for the high frequency of infections associated with these disorders.
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Course Section: 10. Plasma Cell Dyscrasias
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