This is an area in the bone marrow of another patient with MM. There are normal-appearing plasma cells with basophilic cytoplasm and well-developed Golgi apparatus accompanied by large, young plasma cells with light-staining cytoplasm. The type of plasma cells varies greatly from patient to patient; there is also variability of cells in the same patient. When they occur in nests, plasma cells tend to press against each other. It never has been clearly shown that the morphology of plasma cells has any correlation with response to treatment or survival time.
Course Section: 10. Plasma Cell Dyscrasias
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