This is the marrow of a patient with acute leukemia after recovery with chemotherapy. Usually the marrow is nondiagnostic until three or four weeks after termination of treatment. A full response is marked by less than 5% blasts in the bone marrow. Many NRBCs may be present because of rebound after suppression by the toxic drugs. For a week or two after termination of chemotherapy, it is difficult to interpret the bone marrow, since the bone marrow may contain many young cells. It is impossible then to determine if the marrow still contains leukemic blasts, or if the young cells represent recovery of normal cells.
Course Section: 09. Acute Myelomonocytic Leukemia - Monocytic Leukemia - and Erythroleukemia
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