The cell on the left is an E4 cell (polychromatic megaloblast) and the one on the right an E4 cell (polychromatic normoblast) from the marrow of a normal person who was a subject for a control bone marrow culture. Here the differences are marked. The two cells have about the same amount of hemoglobin, but the E4 cell on the left is larger and the nucleus is stained much lighter. It is at this stage of maturation that most morphologic abnormalities appear in the erythrocytic series.
Course Section: 05. Nucleated Red Blood Cells
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