The cell on the left is an E1 cell (promegaloblast) from the bone marrow of a patient with pernicious anemia. The large cell on the right indicated by the arrow is an E1 cell (pronormoblast) from a patient with primary refractory anemia. At this stage of maturation it is impossible to say from these single cells that one is megaloblastic and that the other is not. Both are large cells with fine nuclear chromatin and basophilic cytoplasm.
Course Section: 05. Nucleated Red Blood Cells
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