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Slide 8
Often the megakaryocytes are small in patients with CML; sometimes they are no larger than a promyelocyte. Their number may not be known until the bone marrow is looked at with high magnification. The cell indicated by the arrow is a small granular megakaryocyte with two nuclei. This is not a megakaryoblast since the cytoplasm is granular. This kind of megakaryocyte is not seen in the bone marrow of normal persons, but it is seen in many hematologic disorders.

HEMATOLOGY
Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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