Often the megakaryocytes are small in patients with CML; sometimes they are no larger than a promyelocyte. Their number may not be known until the bone marrow is looked at with high magnification. The cell indicated by the arrow is a small granular megakaryocyte with two nuclei. This is not a megakaryoblast since the cytoplasm is granular. This kind of megakaryocyte is not seen in the bone marrow of normal persons, but it is seen in many hematologic disorders.
Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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