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Slide 20
Before demonstrating AML, we first must know how to recognize myeloblasts and promyelocytes. The cell in this field is a myeloblast. The nucleus-to-cytoplasm (N:C) ratio is about 7:1. The nuclear chromatin is fine, evenly dispersed, and stained light. There are six light-colored nucleoli. The myeloblasts may have one to six light blue nucleoli. The cytoplasm is basophilic and contains no granules. The outside rim of the cytoplasm stains dark, and there is a light perinuclear zone.

Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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