The myeloblasts in this slide contain large cytoplasmic vacuoles. Such vacuoles may be seen in any type of acute leukemia, including the lymphocytic varieties. The vacuoles seen in acute leukemia are probably digestive or lipid vacuoles. It is impossible to identify the source of the vacuoles from blood smears, but their presence is significant and should be reported.
Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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