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Slide 29
The cell indicated by the arrow has a red body called an Auer rod in its cytoplasm. Auer bodies, usually rod-shaped, are derived from malformation of azurophilic granules. They stain positively with myeloperoxidase and Sudan black B. They are present in 15%-25% of patients with ANLL. Because Auer rods are diagnostic of ANLL, blood and bone marrow should be searched carefully for them. Their presence has been associated with a more favorable response to chemotherapy.

HEMATOLOGY
Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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