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Slide 27
This is the blood smear from the same patient with APL as in slide 26. The cells resemble monocytes, which may result in misdiagnosis of AMoL or AMML. These cells have folded, irregular nuclei, and the granules are not as prominent as those in the bone marrow. Since DIC is often associated with APL, the blood smear should be observed carefully for the presence of platelets and for changes in the red blood cells characteristic of microangiopathic hemolytic anemia.

HEMATOLOGY
Course Section: 08. Myelocytic Leukemia: Chronic and Acute
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