Usually the center of a bone marrow particle is too thick and has too much stroma for a differential count. Many times the best area is seen adjacent to the main clump but not in it. At times, the best area is in the thinner part of the particle, as is seen in this slide. Often cells are well-stained at the edge of the bone marrow spread, similar to the feather edge of a blood slide. Such areas are not good for differential counting because the distribution is not the same as in or near the particle itself.
Course Section: 06. Microscopic Examination of the Bone Marrow
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