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Slide 10
The bone marrow should first be scanned for cellularity with the low power objective in the thickest part of the slide. The cellularity is estimated both by the number of cells seen and by the amount of fat and fibrous material. The fat leaves empty spaces as it is dissolved by the alcohol in the stain. You can only estimate cellularity if you have a particle. You cannot estimate it if no clump is present. Cellularity is easier to assess on a biopsy specimen stained and fixed as a tissue than it is on an aspirate. However, it is useful to have some idea of cellularity when you are studying the slide.

Course Section: 06. Microscopic Examination of the Bone Marrow
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