After determining the cellularity and number of megakaryocytes in the center of the marrow particle, look for a good area for a differential count. The first and most important step in making a diagnosis from a bone marrow is to find a good area. The one we see here is poor. The mature red cells are clumped and the white cells are not well-spread. This sample appears to be more likely sinusoidal blood than bone marrow proper.
Course Section: 06. Microscopic Examination of the Bone Marrow
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