This slide was made from the blood of a patient with homozygous hemoglobin C disease. In this condition there are many target cells as well as spherocytes. The target cell in stained preparations is a cell with hemoglobin on the edge, a light area, and more hemoglobin in the center. With scanning electron microscopy it appears to be bell-shaped. Target cells may be seen in small numbers in any type of anemia, but are seen in gretest numbers in liver disease, thalassemia, and hemoglobinopathies. They also may be artifactual due to slight pH changes in the glass slide. If they are seen in only one area on the slide they are probably not true target cells but represent artifacts.
Course Section: 01. Description of Red Blood Cells
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