This slide shows Price-Jones curves. The curves published in 1933 are not generally used at present, but they are being revived by one of the companies manufacturing an automated differential counter. The method for measuring cell diameter is described in Price-Jones' original publication (see suggested readings). On the left is a curve of the diameters of cells from patients with iron deficiency (solid line) compared to cells from normal persons (broken line). Note the height of the curve is lower than the normal, the average diameter is shifted to the left, and the broader base reflects the variation in the diameters. The red cell diameters in patients with pernicious anemia (on the right side of the slide) have a greater than normal diameter and a much broader base than the normal.
Course Section: 01. Description of Red Blood Cells
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