This blood was obtained from a severly burned patient. There are many microspherocytes. The red cells have been damaged by direct heat. In summary, spherocytes are most often seen in patients with hereditary spherocytosis and autoimmune hemolytic anemias. As demonstrated previously, they may be present in great numbers in patients with burns and thermal sensitivity. They may be present in hemoglobinopathies, especially those of hemoglobin C, pernicious anemia, myelofibrosis, leukemia, and even in small numbers in normal blood.
Course Section: 01. Description of Red Blood Cells
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