The cells with scalloped edges seen on this slide are crenated cells or echinocytes. The cells have small, regularly spacced scallops at the periphery. Echinocytes may also have evenly spaced, sharp points instead of scallops. The main cause of crenation is trauma during preparation of the blood film. Crenated cells are seen in normal as well as abnormal blood and more often in old blood than fresh, in thick films more than thin, and after exposure to hypotonic solutions and lytic agents.
Course Section: 01. Description of Red Blood Cells
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